Mechano-Regulation of Fibroblast Function

Authored by: James H.-C. Wang , Bhavani P. Thampatty

Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition

Print publication date:  May  2008
Online publication date:  May  2008

Print ISBN: 9781420078022
eBook ISBN: 9781498761437
Adobe ISBN:

10.1081/E-EBBE2-120041691

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Abstract

This entry will review the mechano-regulation of fibroblast function, with a focus on the effects of mechanical forces on extracellular matrix (ECM) gene expression and protein synthesis, and will also address the interactions of mechanical loads with growth factors and cytokines in terms of their effects on the ECM and tissue engineering constructs.

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