Connecting Exposure to Outcome: Exposure Assessment

Authored by: Adam A. Szpiro

Handbook of Environmental and Ecological Statistics

Print publication date:  September  2017
Online publication date:  January  2019

Print ISBN: 9781498752022
eBook ISBN: 9781315152509
Adobe ISBN:


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The objective in environmental epidemiology is to quantify the association between an environmental exposure and a health outcome measure, in a population under study, with the intention of generalizing to the population at large or to sub-groups of interest. The standard approach is to fit a regression model with health outcomes yi and corresponding exposures xi for subjects i = 1,…,n with additional health model covariates z i = (zi 1,…,zip ) ∈ ℝ p , including an intercept. For example with a continuous outcome we might fit the linear model, 25.1 y i   =   x i β + z i β z +   ∈ i ,

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