Power and Sample Size for Case-Control Studies

Authored by: Mitchell H. Gail , Sebastien Haneuse

Handbook of Statistical Methods for Case-Control Studies

Print publication date:  July  2018
Online publication date:  June  2018

Print ISBN: 9781498768580
eBook ISBN: 9781315154084
Adobe ISBN:

10.1201/9781315154084-9

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Abstract

Protocols for case-control studies usually require a statistical calculation of the required sample size and power of the proposed study. To some this may seem to be a perfunctory exercise. However, in order to compute power or required sample size, one must understand the objectives of the study, the measurements to be used, the hypotheses to be tested, and the planned statistical analysis. Indeed, one can often learn a lot about the proposed study by reading the section on sample size first.

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