ABSTRACT
Photobiomodulation (PBM) also known as low-level laser (light) therapy (LLLT) is approaching its 50th anniversary [1]. LLLT was originally discovered by Endre Mester working in Hungary, who was trying to repeat an experiment described by Paul McGuff in Boston. McGuff had used the newly discovered ruby laser to cure experimental tumors implanted in Sy rian hamsters [2, 3]. However, Mester’s laser only had a small fraction of the power possessed by McGuff’s laser and was insufficient to cure any tumors. Nevertheless Mester observed that the skin wounds that had been made during implantation of the tumors healed better in laser treated animals [4, 5]. Since those early days, LLLT has become gradually more accepted in scientific, medical and popular circles, especially as the number of peer-reviewed papers has grown.
