ABSTRACT
Nanodiamond (ND) particles are versatile platforms for nanomedicine therapy and imaging in that they can be scalably produced to carry a broad spectrum of payloads with improved efficacy and safety. This versatility is rooted in the fact that NDs possess a number of key properties that are integrated into a single carrier. Important studies have outlined the chemical and physical properties of faceted ND surfaces that have contributed to their ability to carry several classes of therapeutic compounds, while also mediating marked improvements in magnetic resonance imaging efficacy. 1–5 With regard to drug delivery, NDs have previously been loaded with doxorubicin and were used for intracranial drug delivery to treat glioblastoma. 6 In addition, NDs have been used for applications in breast cancer, liver cancer, bone growth, and other applications in ophthalmology, and anti-inflammation, among others. 5,7–27
