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Handbook of Tumor Syndromes

Edited by: Dongyou Liu

Print publication date:  May  2020
Online publication date:  May  2020

Print ISBN: 9780815393801
eBook ISBN: 9781351187435
Adobe ISBN:

 Cite  Marc Record

Book description

Tumors/cancers are characterized by uncontrolled growths of abnormal cells that extend beyond their usual boundaries and disrupt the normal functions of affected organs and systems. While about 75%?80% of tumors/cancers arise sporadically without a family connection, 20%?25% appear to be familial (including 10%?15% nonhereditary familial tumors [or familial tumors] and 5%?10% hereditary familial tumors [or hereditary tumors]). As nonhereditary and hereditary familial tumors often show both tumor-related and non-tumor-related (or syndromic) symptoms, they are referred to as tumor syndromes (or cancer susceptibility syndromes).

In comparison with sporadic tumors/cancers, tumor syndromes (>300 described so far) tend to occur at a younger age, involve multiple organs and systems, produce multiple (often in a distinct spectrum) and bilateral lesions, form multiple hamartomatous, benign, or precursor lesions; locate in specific site(s), display unique syndromic features, and affect multiple members/generations of a family.

This book provides state-of-art and authoritative coverage of nearly 100 tumor syndromes, with chapters presenting overviews of individual tumor syndromes in relation to their biology, epidemiology, pathogenesis, clinical features, diagnosis, treatment, and prognosis. Featuring contributions from oncologists, clinicians, and specialists, the book offers a reliable, comprehensive reference on tumor syndromes for scholars and students of medicine, dentistry, pharmacology, nursing, public health, and other biomedical disciplines.

Key Features

  • Reviews the biology, epidemiology, pathogenesis, and clinical features of tumor syndromes
  • Contains up-to-date information on the diagnosis and treatment of tumor syndromes
  • Includes expert coverage from leading oncologists and clinicians

Related Titles

J. R. McIntosh, Understanding Cancer: An Introduction to the Biology, Medicine, and Societal Implications of This Disease (ISBN 978-0-8153-4535-0)

P. S. T. Shanmugam, Understanding Cancer Therapies (ISBN 978-1-1381-9815-9)

J. M. Baehring and J. M. Piepmeier, eds., Brain Tumors: Practical Guide to Diagnosis and Treatment (ISBN 978-0-3673-9022-8)

D. Liu, Tumors and Cancers: Endocrine Glands ? Blood ? Marrow ? Lymph (ISBN 978-1-4987-2975-8)

Dongyou Liu, PhD, has worked at several research and clinical laboratories in Australia and the United States for the past three decades, with a focus on molecular characterization of microbial pathogens and detection of human genetic disorders and tumors/cancers. He is the primary author of more than 50 original research and review articles in various peer-reviewed international journals, the contributor of 197 book chapters, and the editor of more than 10 books.

Table of contents

Prelims Download PDF
Chapter  1:  Introductory Remarks Download PDF
Chapter  2:  Aicardi Syndrome and Klinefelter Syndrome Download PDF
Chapter  3:  BAP1 Tumor Predisposition Syndrome Download PDF
Chapter  4:  Congenital Central Hypoventilation Syndrome Download PDF
Chapter  5:  Familial Neuroblastoma Download PDF
Chapter  6:  Pleuropulmonary Blastoma Download PDF
Chapter  7:  Retinoblastoma Download PDF
Chapter  8:  Rhabdoid Tumor Predisposition Syndrome Download PDF
Chapter  9:  Rubinstein−Taybi Syndrome Download PDF
Chapter  10:  Schinzel−Giedion Syndrome Download PDF
Chapter  11:  Schwannomatosis Download PDF
Chapter  12:  Von Hippel−Lindau Syndrome Download PDF
Chapter  13:  Alagille Syndrome Download PDF
Chapter  14:  Constitutional Mismatch Repair Deficiency Syndrome Download PDF
Chapter  15:  Cronkhite−Canada Syndrome Download PDF
Chapter  16:  Familial Adenomatous Polyposis Download PDF
Chapter  17:  Familial Gastrointestinal Stromal Tumor Syndrome Download PDF
Chapter  18:  Hereditary Diffuse Gastric Cancer Download PDF
Chapter  19:  Juvenile Polyposis Syndrome Download PDF
Chapter  20:  Lynch Syndrome Download PDF
Chapter  21:  MUTYH-Associated Polyposis Download PDF
Chapter  22:  Peutz−Jeghers Syndrome Download PDF
Chapter  23:  Serrated Polyposis Syndrome Download PDF
Chapter  24:  Tylosis with Esophageal Cancer Download PDF
Chapter  25:  Bardet−Biedl Syndrome Download PDF
Chapter  26:  Birt–Hogg–Dubé Syndrome Download PDF
Chapter  27:  Bohring−Opitz Syndrome Download PDF
Chapter  28:  Familial Testicular Germ Cell Tumor Download PDF
Chapter  29:  Familial Wilms Tumor and Related Syndromes Download PDF
Chapter  30:  Hereditary Breast and Ovarian Cancer Download PDF
Chapter  31:  Hereditary Leiomyomatosis and Renal Cell Cancer Download PDF
Chapter  32:  Hereditary Papillary Renal Cell Cancer Download PDF
Chapter  33:  Hereditary Prostate Cancer Download PDF
Chapter  34:  Microphthalmia-Associated Transcription Family Translocation Renal Cell Cancer Download PDF
Chapter  35:  Mulibrey Nanism Download PDF
Chapter  36:  Brooke–Spiegler Syndrome Download PDF
Chapter  37:  Currarino Syndrome Download PDF
Chapter  38:  Cutaneous Malignant Melanoma Download PDF
Chapter  39:  Familial Atypical Multiple Mole Melanoma Syndrome Download PDF
Chapter  40:  Familial Chordoma Download PDF
Chapter  41:  Hereditary Multiple Osteochondromas Download PDF
Chapter  42:  Keratitis–Ichthyosis–Deafness Syndrome Download PDF
Chapter  43:  Li−Fraumeni Syndrome Download PDF
Chapter  44:  McCune−Albright Syndrome Download PDF
Chapter  45:  Milroy Disease Download PDF
Chapter  46:  Mosaic Variegated Aneuploidy Syndrome Download PDF
Chapter  47:  Roberts Syndrome Download PDF
Chapter  48:  Rothmund−Thomson Syndrome Download PDF
Chapter  49:  Werner Syndrome Download PDF
Chapter  50:  Xeroderma Pigmentosum Download PDF
Chapter  51:  Carney Complex Download PDF
Chapter  52:  Congenital Adrenal Hyperplasia Download PDF
Chapter  53:  Familial Hyperparathyroidism Download PDF
Chapter  54:  Familial Isolated Pituitary Adenoma Download PDF
Chapter  55:  Familial Non-Medullary Thyroid Carcinoma Download PDF
Chapter  56:  Familial Pancreatic Cancer Download PDF
Chapter  57:  Hereditary Pancreatitis Download PDF
Chapter  58:  Hereditary Pheochromocytoma and Paraganglioma Syndrome Download PDF
Chapter  59:  Mahvash Disease Download PDF
Chapter  60:  Multiple Endocrine Neoplasia Download PDF
Chapter  61:  Pendred Syndrome Download PDF
Chapter  62:  Ataxia Telangiectasia Download PDF
Chapter  63:  Autoimmune Lymphoproliferative Syndrome Download PDF
Chapter  64:  Bloom Syndrome Download PDF
Chapter  65:  Chediak−Higashi Syndrome Download PDF
Chapter  66:  Congenital Amegakaryocytic Thrombocytopenia Download PDF
Chapter  67:  Diamond–Blackfan Anemia Download PDF
Chapter  68:  Down Syndrome Download PDF
Chapter  69:  Dyskeratosis Congenita Download PDF
Chapter  70:  Familial Acute Myeloid Leukemia Download PDF
Chapter  71:  Familial Monosomy 7 Syndrome Download PDF
Chapter  72:  Familial Multiple Myeloma Download PDF
Chapter  73:  Fanconi Anemia Download PDF
Chapter  74:  GATA2 Deficiency Download PDF
Chapter  75:  LPD Associated with Epstein–Barr Virus Infection Download PDF
Chapter  76:  Nijmegen Breakage Syndrome Download PDF
Chapter  77:  Severe Congenital Neutropenia Download PDF
Chapter  78:  Shwachman−Diamond Syndrome Download PDF
Chapter  79:  Sjögren Syndrome Download PDF
Chapter  80:  SRP72-Associated Bone Marrow Failure Syndrome Download PDF
Chapter  81:  Thrombocytopenia-Absent Radius Download PDF
Chapter  82:  Waldenström Macroglobulinemia Download PDF
Chapter  83:  Wiskott–Aldrich Syndrome Download PDF
Chapter  84:  Bannayan–Riley–Ruvalcaba Syndrome Download PDF
Chapter  85:  Basal Cell Nevus Syndrome Download PDF
Chapter  86:  Beckwith–Wiedemann Syndrome Download PDF
Chapter  87:  CBL Syndrome Download PDF
Chapter  88:  CLOVES Syndrome Download PDF
Chapter  89:  Costello Syndrome Download PDF
Chapter  90:  Cowden Syndrome Download PDF
Chapter  91:  Klippel−Trenaunay Syndrome Download PDF
Chapter  92:  Neurofibromatosis Types 1 and 2 Download PDF
Chapter  93:  Noonan Syndrome Download PDF
Chapter  94:  Perlman Syndrome Download PDF
Chapter  95:  Proteus Syndrome Download PDF
Chapter  96:  Schimmelpenning–Feuerstein–Mims Syndrome Download PDF
Chapter  97:  Simpson–Golabi–Behmel Syndrome Download PDF
Chapter  98:  Sotos Syndrome Download PDF
Chapter  99:  Tuberous Sclerosis Complex Download PDF
Chapter  100:  Weaver Syndrome Download PDF
Index Download PDF
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