ABSTRACT

The concept of X-ray computed tomography (CT) was pioneered by Sir Godfrey Hounsfield and Allan McLeod Cormack in the 1970s at the EMI Central Research Laboratories (Middlesex, UK) and Tufts University (Boston, MA), respectively. Their main idea of using multiple projections to create tomographic images formed the basis of the scanner made by Electrical and Musical Industries (EMI), the first clinical brain scanner. Since the days of the first brain scan in the early 1970s, CT has come a long way. Multi-detector computed tomography (MDCT) has seen a steady increase in capabilities, availability, and dedicated protocols for various applications (see Section III, Chapter 32). One such application is imaging of temporally evolving processes (e.g., imaging flow dynamics in blood vessels), an application that is usually referred to as 4D or dynamic imaging.