ABSTRACT
Studies on computer analysis of medical images began in the 1960s (Winsberg et al. 1967). However, extensive research under the concept of computer-aided diagnosis (CAD) on mammograms and other medical images started in the 1980s (Chan et al. 1987, 1988) (see Section IV, -->Chapter 59). Since the first FDA approval of the commercial system and the Medicare reimbursement, computer-aided detection (CADe) systems for breast masses and microcalcifications on mammograms have been widely used in clinical practice. Many studies have been published on the utility of CADe in prospective studies (Freer and Ulissey 2001; Birdwell et al. 2005). On the other hand, research topics have been shifted from lesion detection to lesion classification, density measurement for cancer risk analysis, prognostic estimation for treatment response, and development of digital and 3D phantoms. In this chapter, we introduce recent broad research topics on computer analysis of mammograms.
