ABSTRACT

There are interesting algorithmic issues that arise when length constraints are taken into account in the formulation of a variety of problems on string similarity, particularly, in the problems related to local alignment. These types of problems have their roots and most striking applications in computational biology. In fact, because of the applications in biological sequence analysis, detection of local similarities in two given strings has become an increasingly important computational problem. When there are additional constraints that need to be satisfied as a part of the search criteria, it is natural to consider approximation algorithms for the resulting computational problems for large parameters.