Advances in Fluorescence Spectroscopy and Imaging

Authored by: Schneckenburger Herbert , Frank J. Gunn-Moore , Weber Petra , Bruns Thomas , Wagner Michael

Handbook of Photonics for Biomedical Science

Print publication date:  May  2010
Online publication date:  May  2010

Print ISBN: 9781439806289
eBook ISBN: 9781439806296
Adobe ISBN:

10.1201/9781439806296-c4

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Abstract

This chapter describes advanced methods of fluorescence imaging and in vitro diagnostics with some emphasis on wide-field microscopy with high spatial, spectral, and temporal resolution. Applications are concentrated on tumor diagnosis by autofluorescence, measurements of cholesterol dependent membrane dynamics, and detection of intermolecular interactions in pathogenesis of Alzheimer’s disease as well as in sensing of apoptosis.

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