Ion channels in pain

Authored by: J.P. Johnson Jr

Handbook of Ion Channels

Print publication date:  February  2015
Online publication date:  February  2015

Print ISBN: 9781466551404
eBook ISBN: 9781466551428
Adobe ISBN:

10.1201/b18027-46

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Abstract

Pain signaling is largely accomplished by neurons, and ion channels are critical for the function and signaling of all neurons. Neuronal signaling is a complex synthesis of the conductances of many channels and transporters, and all of the channels in the neurons of the pain pathway play some role in pain signaling. This chapter will introduce the basic pathways of pain signaling and discuss a few ion channels that have been most studied and most closely linked to pain.

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