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Handbook of Small Animal Imaging

Preclinical Imaging, Therapy, and Applications

Edited by: George C. Kagadis , Nancy L. Ford , Dimitrios N. Karnabatidis , George K. Loudos

Print publication date:  April  2016
Online publication date:  February  2016

Print ISBN: 9781466555686
eBook ISBN: 9781466555693
Adobe ISBN:

10.1201/b19052
 Cite  Marc Record

Book description

The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans.

Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research.

The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.

Table of contents

Chapter  1:  Defining Small Animal Imaging, Therapy, and Applications Download PDF
Chapter  2:  Ethics and Regulations for Research with Animals Download PDF
Chapter  3:  Small Animal Handling, Care, and Anesthesia Download PDF
Chapter  4:  Preclinical Models Download PDF
Chapter  5:  Microcomputed Tomography Download PDF
Chapter  6:  Digital Subtracted Angiography of Small Animals Download PDF
Chapter  7:  Single-Photon Emission Computed Tomography Download PDF
Chapter  8:  Positron Emission Tomography Download PDF
Chapter  9:  MR Imaging Download PDF
Chapter  10:  Optical Imaging Download PDF
Chapter  11:  Optical-CT Imaging Download PDF
Chapter  12:  PET/CT Download PDF
Chapter  13:  Introduction to Combining MRI with PET Download PDF
Chapter  14:  Exotic Imaging Approaches Download PDF
Chapter  15:  X-Ray, MRI, and Ultrasound Agents Download PDF
Chapter  16:  Radiochemistry for Preclinical Imaging Studies Download PDF
Chapter  17:  Molecular Targets and Optical Probes Download PDF
Chapter  18:  Developing Technologies for Small Animal Radiotherapy Download PDF
Chapter  19:  Dosimetry of Ionizing Radiation in Small Animal Imaging Download PDF
Chapter  20:  Treatment Planning for Small Animals Download PDF
Chapter  21:  Radiolabeled Agents for Molecular Imaging and/or Therapy Download PDF
Chapter  22:  Quantification in Nuclear Preclinical Imaging Download PDF
Chapter  23:  Performance Assessment of Small Animal Imaging Systems and Common Standards Download PDF
Chapter  24:  Monte Carlo Simulations in Imaging and Therapy Download PDF
Chapter  25:  Small Animal Imaging and Therapy Download PDF
Chapter  26:  Applications for Drug Development Download PDF
Chapter  27:  Imaging of Intracellular Targets Download PDF
Chapter  28:  Imaging of Cell Trafficking and Cell Tissue Homing Download PDF
Chapter  29:  Imaging of Cardiovascular Disease Download PDF
Chapter  30:  Imaging Angiogenesis Download PDF
Chapter  31:  Imaging of Hypoxia, Apoptosis, and Inflammation Download PDF
Chapter  32:  Vessel Wall Imaging Download PDF
prelims Download PDF
Index Download PDF
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