Abstract

With the rapid development of nanotechnology in the past decade, chemical/biological sensors using graphene materials have attracted significant attention for chemical, genomics, biomedical diagnostics, and drug discovery applications. Graphene-based chemical/biological devices with high sensitivity, low decreased energy consumption, and potentially highly miniaturized integration have gradually developed in conventional sensing technologies. Due to their particular structure and excellent properties, including high specific surface area, outstanding electrical conductivity, and high chemical stability, graphene has become the promising material for the development of new types of chemical/biological sensors. In this chapter, we mainly introduce the basic concept, configuration, working mechanism of graphene-based transistor sensors, and their applications in ultrasensitive detection of chemical/biological entities, such as poisonous gases, nucleic acids, proteins, and cells.