ABSTRACT

Dientamoeba fragilis is a pathogenic protozoan of the human gastrointestinal tract with a worldwide distribution. 1–4 First described in 1918 by Jepps and Dobell, 5–7 it has emerged as an important and misdiagnosed cause of chronic gastrointestinal illnesses such as diarrhea and “irritable-bowel-like” gastrointestinal disease. 8–12 Almost a century after its observation, and although it has been described around the world, there are still doubts about its life cycle, prevalence, pathogenicity, and treatment.