ABSTRACT

The current chapter provides an overview of the current state of the literature on the neurogenetics of psychopathy and, to a lesser extent, broader AB. We identify key neural mechanisms linked to emotional and behavioral deficits that characterize psychopathy, which may differentiate psychopathy from broader AB and examine additional risk factors (i.e., genetic variation, environment) associated with psychopathy, including the evidence from studies that have begun to examine the interplay of these factors (e.g., G × E interaction models, neurogenetics pathways) in the development of psychopathy and AB more broadly. Finally, to motivate future research in this emerging field, we provide an imaging gene-by-environment (IG × E) interaction model of psychopathy that integrates current research on genetic and environmental influences on psychopathy and AB via brain function.