ABSTRACT

As we close this volume, we believe that a few points need to be made – a sort of summary if you will. Because the authors in each chapter have done such a great job of summarizing the field in each of their areas, this chapter will be rather more of a 30,000ʹ overview of the whole field. It was not long ago that many of us hoped that understanding the underlying systems genetics of any trait would be as easy as understanding the gene polymorphisms present in different individuals, a view captured and forever immortalized in pop culture in the movie “Gattaca.” However, one thing that is clear from the previous chapters is that we are not working in the “genetics” of 40 years ago; i.e., to paraphrase an automobile advertisement from several years ago, “This is not your Father’s (or Gattaca’s) genetics!”